Abstract:
Results of a study of lipid peroxidation, antioxidant system components, and cholinergic neurotransmitter system in the organs
of experimental rats of different ages exposed to alimentary synthetic estrogen are presented. Given the state of peroxidation processes and AChE activities in female rats exposed to xenoestrogen, it is possible to assume the possibility of the restructuring of
the functioning of mediator and enzyme systems and additional
strengthening of pathological symptoms. In the future, such phenomena may trigger the reduction of potential of compensatory
mechanisms in compromising the health of the consumers. In
puberty, females were more sensitive to nutritional synthetic estrogen than mature animals, thus proving that age is another factor in xenoestrogen exposure. Because of the changes in the rates
of reactions to detoxification but not to the metabolism of estrogen received into the organism, particularly with food, with age
the animals were less susceptible to the effects of these substances
